Uffner & Liu is a contemporary art gallery on New York City's Lower East Side. Founded by Rachel Uffner in September 2008, the space opened with a mission of supporting multi-generational artists working in a variety of media. Over the past 17 years, the gallery has established itself as a vital platform for introducing new artistic voices, championing female-identifying artists, and cultivating institutional relationships.

The gallery began in a modest storefront on Orchard Street before relocating to a significantly larger space on Suffolk Street in March 2014, which was further expanded in the summer of 2019. Today, Uffner & Liu occupies a two-floor, 5,000 square-foot building featuring three exhibition spaces, abundant natural light, and 20-foot ceilings—an expansive setting that encourages artists to push the boundaries of their practices.

In 2025, Gallery Director Lucy Liu joined as Partner, ushering in a new chapter under the name Uffner & Liu. Together, the partners continue the gallery’s founding ethos while introducing new perspectives, deepening curatorial programming, and expanding its international reach.